Toward a Biology Worthy of Life > Natural Genome Remodeling > Brief excerpt
A project by Stephen L. Talbott

Mutations are not accidents

It is no wonder, then, that when genomic researcher David Haussler of the University of California, Santa Cruz, was asked by the journal Cell what has been most surprising about the human genome, one of the things he cited was “mounting evidence” that transposons “play a critical role” in the turnover and reinvention of regulatory elements in DNA. And, responding in Science to a report about the work on jumping genes in mammalian brains, Southern Illinois University neuroscientist, David King, wrote that the “dismissive dictum, ‘Mutations are accidents’, has grown obsolete”, adding that protocols for “the spontaneous, non-accidental production of genetic variation are deeply embedded in genomic architecture”.

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