Titles of All Reports
A group of transgenic barley plants expressing the bar selectable
marker gene did not produce viable offspring.
Adoption of GM Cotton Slowing in West Africa
Due to Concerns About Inferior Qualities of Crop
After Reported 2018 Birth of Two Genetically-Engineered Babies in China,
Calls for Moratorium on Human Germline Engineering Grow
Alfalfa with corn transgenes for anthocyanin (red-purple pigment)
production was not visibly altered or changed dependent on light and
Apples over-expressing a fruit-ripening enzyme lacked flowers and had
malformed stomata and altered composition of cell walls.
Atlantic salmon expressing transgenic growth hormone experienced
numerous changes to their cardiorespiratory system.
Atlantic salmon fed Bt corn had altered enzyme activity in liver
and intestine as well as altered proportions and numbers of different
white blood cells.
Barley with the transgene for a heat-stable enzyme showed highly variable
levels of the enzyme, an anomalous distribution of expression in the
grain, and dramatically reduced weight of individual grains.
Bt cotton had altered protein metabolism and produced less
insecticidal toxin in leaves when subjected to high temperatures during
Bt cotton showed decreased ability to kill cotton bollworm
larvae during flower development and flowering.
Bt maize had changed lipid composition in stems; also, lipid
composition in soil was altered, and soil respiration was reduced.
Bt maize has higher lignin content.
Bt maize varieties matured more slowly and had on average lower
grain yield and higher grain moisture content than conventional varieties.
Bt rice showed signs of dwarfism and other abnormalities.
Byproducts from Bt maize enter streams, and in feeding experiments
affected stream insects.
Canola plants over-expressing a bacterial phytoene synthase gene also
had a reduced level of chlorophyll, changed structure of plastids,
changed composition of fatty acids, and delayed germination.
Conventional, certified canola seedlots were contaminated with genetically
Cotton plants and seeds expressing Bt toxin were found in non-Bt refuges.
CRISPR-Cas9, Popular New GMO Tool, Can Cause Extensive Genomic Damage,
British Researchers Report
Dandelions manipulated to have compound leaves showed irregular leaf
form and did not flower.
Detection of GMOs in non-GM food and feed imports
Diet containing glyphosate-resistant soybeans affected the nuclei of
liver cells in mice.
Difficulties were encountered when trying to express human collagen
Discoloration and DNA rearrangements were observed in transgenic
tobacco plants expressing HIV proteins.
Experimental cross-pollination between transgenic herbicide-resistant
canola and wild field mustard led to highly fertile, herbicide-resistant
wild field mustard.
Fewer wild bees were observed in glyphosate-resistant canola fields.
Field performance of Bt transgenic crops: A review
Flavonol-enriched tomatoes had altered levels of at least fifteen other
Fruiting morphology was altered when glyphosate-resistant cotton was
sprayed with glyphosate.
Genes escaped from cultivated GM rice to its weedy and wild relatives.
Genetically Manipulating Rabbits to Increase Meat Production
Caused Enlarged Tongues and Severe Health Problems.
Genetically modified atlantic salmon/brown trout hybrids have unexpected
Genetically modified insect-resistant rice and weedy rice hybrids
have increased seed production.
Glyphosate-resistant cotton showed abnormal reproductive development when
sprayed with glyphosate.
Glyphosate-resistant GM soybeans differ compositionally from non-GM
soybeans and contain high residues of the herbicide glyphosate.
Glyphosate-resistant soybeans had lower yields.
Glyphosate-resistant soybeans have altered root nodules when
sprayed with glyphosate.
Glyphosate-resistant sugar beet production alters population densities of
some arthropods, significantly reducing the number of bees and butterflies
in beet fields.
Glyphosate-resistant sugar beets became more susceptible to root rot when
sprayed with glyphosate.
GM cotton and suicide rates.
GM Maize Differs from Non-GM Maize at Molecular Level
In Unintended Ways, Including in Response to Drought Stress.
GMO Semi-Dwarf Poplar Trees May Be More Susceptible to Pests
GM wheat outcrosses more often than unmodified wheat of the same
Herbicide-resistant canola volunteers were still detected after ten years
of stringent control.
Herbicide-resistant soybean plants were shorter, with less chlorophyll,
lower weight, and increased susceptibility to stem-splitting at high
High rate of unintended mutations in Arabidopsis plants genetically
engineered with CRISPR/Cas9 method.
Increased planting of glyphosate-resistant crops and application of
glyphosate causes increase in glyphosate-resistant weed species.
Increased resistance to Bt toxin is found in some populations of
cotton bollworm (Helicoverpa zea).
Increasing resistance of pests to genetically modified, insect-resistant
Innate Immunity is Affected in Insect-Resistant GM Aspens
Insect-resistant, transgenic cotton was more susceptible to fungal disease
than its parent line.
Insect-resistant transgenic potatoes had less foliage and altered
levels of leaf-glycoalkaloids.
Insertion of transgenes in oats resulted in modification of both the
transgenic construct and host DNA.
Inulin-storing potatoes had higher alkaloid content and pigs fed on them
had reduced daily weight gain.
Leaf litter from insect-resistant transgenic trees causes changes in
aquatic insect community composition.
Long-term toxicity of a Roundup herbicide and a Roundup-tolerant
genetically modified maize.
Monarch butterfly larvae exposed to anthers from Bt maize ate
less and gained less weight.
New CRISPR genetic engineering technology caused large number
of unintended mutations, researchers in mouse study conclude
New GMO Rice Lines in India Are High in Vitamin A Precursor,
But Unfit for Cultivation Due to Low Yield and Lack of Plant Vigor
New Studies Fail to End Controversy about How to Interpret Last Year’s
Surprise Results in U.S. Human Embryo Research
Overexpression of phytoene synthase gene in Arabidopsis resulted
in delayed germination, increased levels of chlorophyll, and changes in
relative levels of carotenoids.
Peas engineered to be weevil-resistant elicited immune reactions in mice.
Peas engineered to be weevil-resistant had lowered starch digestibility
when fed to chickens and pigs.
Perspective matters: Bias and conflict of interest in studies about
genetically modified organisms.
Pheromone-producing GM wheat does not repel pests in field trials.
Pineapple plants with transgenes for fungus and herbicide resistance
had altered biochemical make-up.
Plant height and flowering were altered in alfalfa genetically
engineered to reduce lignin content.
Plants producing a biodegradable polyester were smaller, never produced
seeds and showed severe changes in metabolism.
Potatoes genetically modified to store more starch stored less starch.
Potatoes with altered sugar metabolism had changed levels of many
metabolites, some not thought to be associated with sugar metabolism.
Potatoes with transgene for virus resistance were variably resistant, and
some lines without the target gene nevertheless became highly
Potential unintended effects of RNAi-based insecticidal crops.
Researchers Agree Human Embryo Experiment Generated Unintended Effects,
But Disagree on How to Interpret Surprise Results
Root colonization of glyphosate-resistant soybeans by pathogenic
Fusarium fungi increased with glyphosate application.
Root nodule bacteria with Bt transgene tended to displace
non-manipulated bacteria in legume root nodules.
Sheep growth hormone expression was highly variable in transgenic pigs,
whose bodies had more protein and water and less fat.
Single-site integration of foreign DNA into Arabidopsis showed
rearrangements and deletions of both plant DNA and foreign DNA.
Spread of herbicide-resistance from genetically modified creeping
bentgrass into the wild.
Spring wheat with scab-resistance transgene was not scab-resistant and
showed localized death of leaf tissue.
Sugarcane engineered to reduce polyphenol oxidase (PPO) activity had
greater PPO activity, even without the transgene.
Sugarcane plants with lectin transgene for stemborer resistance showed
Suppression of DHS enzyme in Arabidopsis (a mustard plant) was associated
with enlarged leaves, greater root mass, and enhanced seed yield.
Suppression of DHS gene in tomatoes
was associated with lack of fruiting, altered leaf morphology, higher
rate of photosynthesis and other changes.
Tilapia fish engineered for transgenic expression of growth hormone
had deformed heads and backs, atrophied gonads, and lower mineral content.
Tomato plants overexpressing phytoene synthase gene were stunted in growth.
Traditional Non-GMO Cotton Can Yield Economic Benefits Similar to GMO
Cotton on Non-Irrigated Small Farms in India
Transgene in corn, intended to raise iron availability, also changed
levels of other minerals and proteins.
Transgenes that have escaped from glyphosate-resistant canola can persist
in the wild.
Transgenic barley plants over-expressing a zinc transport protein
had smaller seeds and did not accumulate more zinc when grown in
Transgenic birch trees expressing an antifungal enzyme from sugarbeets
showed increased susceptibility to leaf spot disease in the field.
Transgenic coho salmon expressing growth hormone had enlarged heads,
reduced viability, and accelerated development of their life cycle.
Transgenic DNA from glyphosate-resistant soybeans was detected in the
intestinal flora of humans.
Transgenic expression of a disease-resistance gene activated the
oxidative-stress response in rice.
Transgenic expression of a mouse milk protein impaired mammary
development and function in pigs.
Transgenic expression of growth hormone in coho salmon led to a narrower
body, more red muscle mass, and smaller white muscle fibers.
Transgenic expression of sheep growth hormone in sheep increased
the incidence of reproductive problems and premature death.
Transgenic goats engineered to secrete the human protein cholinesterase
into their milk produced less milk, with lower fat and lactose levels
and unusually high white blood cell counts.
Transgenic pigs expressing bovine growth hormone had lower appetites,
enlarged organs, gastric ulcers, and other health problems.
Transgenic pigs with elevated levels of growth hormone were
infertile, pre-diabetic, and experienced joint problems.
Transgenic sequences of some Bt maize plants have changed since
they were approved.
Transgenic sheep had unusually high morbidity and expressed a
milk-specific protein in their spleen, liver, and other organs.
Transgenic tobacco with resistance to bleaching herbicides had altered
composition of carotenoids.
Transgenic tomatoes altered with a marker gene construct showed
significant changes in morphological and physiological characteristics.
Unintended changes in gene expression were observed in Arabidopsis
plants engineered for resistance to the herbicide glufosinate.
Unintended Effects of Herbicide-Resistance Genes on Crop Yield.
Using CRISPR-Cas9 to Engineer Resistance to Virus in Cassava Plants
Using CRISPR-Cas9 to Genetically Engineer Human Therapies
Could Pose Increased Risk of Cancer, Two Studies Suggest.
Western Corn Rootworm Not Killed by Bt Corn in Iowa.
Western corn rootworms were found feeding on volunteer corn plants
expressing a Bt toxin specific to that pest.
Wheat expressing transgenic glutenin shows reduction in yield, varying
production of glutenin, and altered morphology.
Wheat transformed with a high-molecular-weight glutenin gene showed
irregular expression of glutenin and changed its expression levels over
Wheat with transgene for low-molecular-weight glutenin showed anomalies
in glutenin production and some plants had reduced levels of other
Why GM bacteria haven’t succeeded in the real world:
It’s the context, not only the genes.
Wild sunflowers with transgene for Bt toxin produced more seeds than
normal wild sunflowers.
Yield differences between insect-resistant Bt rice and non-GM rice.