Type of Unintended Effect: Morphological (Animals)
atlantic_salmon_001:
Atlantic salmon expressing transgenic growth hormone experienced
numerous changes to their cardiorespiratory system.
coho_salmon_001:
Atlantic salmon expressing transgenic growth hormone experienced
numerous changes to their cardiorespiratory system.
coho_salmon_002:
Transgenic coho salmon expressing growth hormone had enlarged heads,
reduced viability, and accelerated development of their life cycle.
pig_001:
Transgenic pigs expressing bovine growth hormone had lower appetites,
enlarged organs, gastric ulcers, and other health problems.
pig_002:
Sheep growth hormone expression was highly variable in transgenic pigs,
whose bodies had more protein and water and less fat.
pig_003:
Transgenic pigs with elevated levels of growth hormone were
infertile, pre-diabetic, and experienced joint problems.
pig_004:
Transgenic expression of a mouse milk protein impaired mammary
development and function in pigs.
sheep_001:
Transgenic expression of sheep growth hormone in sheep increased
the incidence of reproductive problems and premature death.
tilapia_001:
Tilapia fish engineered for transgenic expression of growth hormone
had deformed heads and backs, atrophied gonads, and lower mineral content.
Type of Unintended Effect: Morphological (Plants)
alfalfa_002:
Plant height and flowering were altered in alfalfa genetically
engineered to reduce lignin content.
apple_001:
Apples over-expressing a fruit-ripening enzyme lacked flowers and had
malformed stomata and altered composition of cell walls.
arabidopsis_001:
Plants producing a biodegradable polyester were smaller, never produced
seeds and showed severe changes in metabolism.
arabidopsis_002:
Suppression of DHS enzyme in Arabidopsis (a mustard plant)
was associated with enlarged leaves, greater root mass, and enhanced
seed yield.
barley_001:
Barley expressing a heat-stable enzyme showed highly variable expression
of the enzyme, an anomalous distribution of expression in the grain,
and dramatically reduced weight of individual grains.
barley_002:
Transgenic barley plants over-expressing a zinc transport protein
had smaller seeds and did not accumulate more zinc when grown in
zinc-deficient soil.
canola_001:
Canola plants over-expressing a bacterial phytoene synthase gene also
had a reduced level of chlorophyll, changed structure of plastids,
changed composition of fatty acids, and delayed germination.
cotton_004:
Glyphosate-resistant cotton showed abnormal reproductive development when
sprayed with glyphosate.
cotton_005:
Fruiting morphology was altered when glyphosate-resistant cotton was
sprayed with glyphosate.
dandelion_001:
Dandelions manipulated to have compound leaves showed irregular leaf form
and did not flower.
potato_004:
Insect-resistant transgenic potatoes had less foliage and altered levels
of leaf-glycoalkaloids.
rice_002:
Bt rice showed signs of dwarfism and other abnormalities.
soybean_001:
Herbicide-resistant soybean plants were shorter, with less chlorophyll,
lower weight, and increased susceptibility to stem-splitting at high
temperatures.
sugarcane_001:
Lectin transgene for stemborer resistance alters growth of sugarcane.
tobacco_002:
Discoloration and DNA rearrangements were observed in transgenic
tobacco plants expressing HIV proteins.
tomato_001:
Tomato plants overexpressing phytoene synthase gene were stunted in growth.
tomato_003:
Suppression of DHS gene in tomatoes was associated with lack of
fruiting, altered leaf morphology, higher rate of photosynthesis and
other changes.
tomato_004:
Transgenic tomatoes altered with a marker gene construct showed
significant changes in morphological and physiological characteristics.
wheat_003:
Spring wheat with scab-resistance transgene was not scab resistant and
showed localized death of leaf tissue.
wheat_004:
Wheat expressing transgenic glutenin shows reduction in yield, varying
production of glutenin, and altered morphology.